TRUST4¶
Description¶
Tcr Receptor Utilities for Solid Tissue (TRUST) is a computational tool to analyze TCR and BCR sequences using unselected RNA sequencing data, profiled from solid tissues, including tumors. TRUST4 performs de novo assembly on V, J, C genes including the hypervariable complementarity-determining region 3 (CDR3) and reports consensus of BCR/TCR sequences. TRUST4 then realigns the contigs to IMGT reference gene sequences to report the corresponding information. TRUST4 supports both single-end and paired-end sequencing data with any read length.
More information¶
- Homepage: https://github.com/liulab-dfci/TRUST4
Availability¶
Module | NIC5 | Hercules2 | Dragon2 | Lemaitre3 | Dragon1 |
---|---|---|---|---|---|
TRUST4/1.0.6-GCC-11.2.0 | ✓ |